if you are asking about flavoring pound cake with citrus, yes. For all baking, the heat and other ingredients will destroy/delute the flavor of the fruit juice. To impart citrus flavor, you must use the oil in the skin of the citrus. That is where the flavor is concentrated, in the oil in the skin. So use organic fruit; wash and dry well. Then zest it taking care not to cut into the white pith as it is bitter.